Vacation rentals with lake access in Alachua County

Find and book unique lake access rentals on Airbnb

Top-rated lake access rentals in Alachua County

Guests agree: these lake access rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

Aerial view of Lake Santa Fe showcases expansive water reflecting the sky, bordered by lush greenery and several docks. The serene landscape is complemented by well-kept lawns and a variety of trees, providing a tranquil setting for outdoor activities.

Home in Melrose

5 out of 5 average rating, 14 reviews

Lakeside Suite

The Lakeside Suite consists of the ENTIRE 1800 SQUARE FOOT BOTTOM FLOOR of our spacious home on Lake Santa Fe. You'll have your own private entrance, facing the lake, a private porch and use of the dock and the beach. We also provide kayaks & canoes and lake access for swimming, sunning and relaxing. Our home is family friendly & it's also a great space for a private getaway or relaxing weekend. Me and my husband live upstairs and we have our own entrance and we're available if you need us.

Guest favorite

A wooden dock extends over the water towards a two-story house, featuring a spacious patio with seating. The grassy area around the house is shaded by trees draped in Spanish moss, contributing to a serene outdoor environment.

Home in Waldo

4.94 out of 5 average rating, 17 reviews

Santa Fe Lake House in Earleton

Come make memories for a lifetime on Santa Fe lake in Earleton . This a great place to stay for Gator events with a 20 minute commute. The house is in a paved neighborhood for walking or biking. Enjoy beautiful sunrises and sunsets with your unobstructed lake view . The house is comfy and cozy for the whole family to come enjoy. Whether you are into water sports, fishing, or just want a nice quiet getaway this place offers it all. Right on lake, with your own private boat ramp, dock and beach

Guest favorite

The living room features comfortable seating arrangements with a dark brown sofa and loveseat, facing a wooden coffee table. A large flat-screen TV is mounted on the wall. Natural light enters through partially closed blinds, and a ceiling fan adds to the space's comfort.

Home in Gainesville

4.88 out of 5 average rating, 68 reviews

Sweet 3/2 Newnans Lake Home

Spacious (1800 sq'), clean home in quiet lakeside neighborhood, 5 miles to downtown and 6 miles to UF & Shands. Well behaved pets and children welcome. The home is at the end of a low traffic street and the back yard is fenced. The house has Wi-Fi, large kitchen, comfy living room, very comfy beds and the Cox Cable sports package with a TV in each room. Also, the home is equipped with a 30A RV hook-up and a Security Alarm system. FYI - The house uses solar energy for most of its electricity.

Top guest favorite

Home in Melrose

5 out of 5 average rating, 13 reviews

Modern LAKE HOUSE on Lake Santa Fe near Gville/UF

Have fun OR relax at this fully renovated LAKE HOUSE w/BOATHOUSE and raised sunset deck only 30 mins to Gainesville! Sit back and and enjoy the beautiful views of the lake as soon as you enter the home or up close from the hammock swings in the boat house! 3 BR/2 BA plus converted air conditioned garage used as a game room with Ping Pong Table and TV, easily sleeping 8. The backyard offers a large deck with privacy fencing and lush landscaping with direct access to step right into the lake.

Superhost

A rustic interior showcases wooden walls and decorative accents. A stylish metal bookshelf holds various items, while two modern bar stools are positioned nearby. The open layout reveals a glimpse of the kitchenette and front door, enhancing the space's inviting ambiance.

Cottage in Earleton

4.93 out of 5 average rating, 14 reviews

Lake Santa Fe Cottage #5b 1BR/1BA/Kitchen Sleeps 3

Spacious 1 BDRM 1 BA lakeside cottage at historic former Buddy's Landing site on Lake Santa Fe. Private and gated with direct lake access. A peaceful, quiet space to unplug and get away from the daily chaos. Use of the private boat launch and on site trailer parking for a small additional fee of $20. Perfect setting for multiple families to hang together on the lake! A GREAT private set-up for travel nurses or business professionals needing monthly rentals. (Message me for special rates)

Superhost

Home in Hawthorne

4.89 out of 5 average rating, 9 reviews

5-Star Luxury Lakefront Resort!

Welcome to your perfect lakeside retreat! This stunning lakefront home offers breathtaking views, direct access to the water, and all the comforts of a modern getaway. With spacious living areas, a fully equipped kitchen, and cozy bedrooms, you’ll feel right at home whether you’re relaxing indoors or enjoying the scenic outdoors. Step out onto the deck to sip your morning coffee, lounge by the BBQ, sit under the beautiful mossy trees, or take a ride on your jet ski, motorboat, or kayak!

Top guest favorite

A charming orange and white cottage is positioned under a large tree, with a grassy area extending around it. The cottage features multiple windows and a porch, while a serene body of water is visible in the background among the trees.

Cabin in Hawthorne

5 out of 5 average rating, 65 reviews

Creek House, connecting Orange&Lockaloosa Lakes

Enjoy Old Florida at its finest! The Creek connects 2 lakes; Orange & Lochloosa, known for outstanding Bass (Bassmasters 1 of the top 10 in US & #1 in SE for Bass) plus Crappie fishing! Use of private dock to keep boat tied. One mile from Marjorie Rawlings historic park is the boat ramp. Local attractions; Historic Micanopy, Island Grove winery, Ocala World Equestrian center 20 miles & 15 miles to UF/Gainesville. Hiking, biking & horse trails nearby. Springs in close driving distance.

Guest favorite

A modern kitchen features light cabinetry paired with dark lower units. A double sink is positioned beneath a window, allowing natural light. The turquoise tile backsplash adds a pop of color. Open shelving displays dishes, and a stainless steel stove is visible.

Apartment in Melrose

4.87 out of 5 average rating, 196 reviews

The Orchid of Lake Santa Fe

Melrose Bay on Lake Santa Fe This apartment is newly remodeled. It features new cabinets, new appliances, a private porch and lovely furnishings, WIFI and cable. Downtown Melrose is in walking distance with three restaurants (one is the famous Blue Water Bay), public library, post office, grocery store, dollar store and Ace. Bring your boat and launch at the nearby boat ramp. Lake Santa Fe is a recreational lake with clean spring fed water for swimming, boating, skiing and fishing.

Guest favorite

Home in Melrose

5 out of 5 average rating, 5 reviews

Lake Santa Fe Estate Home

Forget your worries in this spacious and serene space on beautiful Melrose Bay. Walking distance to the restaurants and shops of downtown Melrose, close to Melrose Bay Park and Lake Santa Fe Park, minutes by car to UF, Keystone Heights and Gainesville. The house boasts beautiful lake views throughout, a spacious modern well stocked kitchen, open and very functional floor plan, large master suite with walk in closets and attached master bath, wonderful screen porch with outside eating.

Superhost

A serene outdoor space features a wooden deck with four Adirondack chairs arranged around a central fire pit. Soft lighting is provided by hanging string lights, enhancing the ambiance. Surrounding trees provide shade and a sense of privacy in the green, grassy area.

Home in Alachua

4.82 out of 5 average rating, 222 reviews

Gated Golf Getaway close to Springs and UF

A clean and comfortable home, situated in a gated community with a public golf course, reasonably priced restaurant, swimming pool (seasonally, quick walk or drive), playground, and tennis courts available to guests. The home features a gas fireplace and screened patio with table, chairs and grill. There are 3 bedrooms each with a queen bed. Located on U.S. highway 441 just 20 minutes from U.F. sports stadiums and Hospitals. Convenient shopping and restaurants 10 minutes by car.

Top guest favorite

A wooden balcony offers a view of a landscaped area filled with lush greenery and mature trees. Soft moss hangs from branches, creating a serene atmosphere. The adjacent building is set back, blending harmoniously with the natural surroundings.

Apartment in Waldo

4.98 out of 5 average rating, 162 reviews

Fernbank on beautiful Lake Alto. Laketime Getaway

Visit this beautiful, tranquil lakeside spot for an amazing getaway. It's a six acre property, an inspiring place to study, write, or get work done with fun things to do while on a break. Swim, kayak, canoe, paddle board or enjoy sitting on the dock. Visit the barn for basketball, ping pong, and corn hole. It's a studio apartment with a private bathroom and beds for four, plus two couches and air beds available. Note: This is an upstairs apartment.

Top guest favorite

A view from the private balcony overlooks Big Lake Santa Fe, showcasing the tranquil water and nearby dock. Lush greenery and Spanish moss drape from the trees, creating a serene backdrop. The sturdy wooden railing frames the picturesque scene.

Apartment in Melrose

4.99 out of 5 average rating, 94 reviews

Lakefront Retreat Apartment Remodeled, Premium Bed

Private lake home on Big Lake Santa Fe is the perfect place to unwind and enjoy gorgeous sunset views. The rental unit is an upstairs separated apartment. It has a cedar interior with a cabin feel has recently been renovated with new appliances, flooring and updated bathroom with walk in shower. Bring your boat to cruise the lake or fish and tie up at our dock. Enjoy swimming, water skiing, fishing or just relaxing on the deck.