Vacation rentals in De Soto

Book unique vacation rentals, houses, and more on Airbnb

Top-rated vacation rentals in De Soto

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

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Superhost

Home in Creston

4.83 out of 5 average rating, 36 reviews

Vine Abode

Welcome to the largest hosting property in Creston! This five-bedroom, two-bath rental offers spacious accommodation with modern amenities. Bedrooms are equipped with five Queen beds and two twin size beds. The house features a fully equipped kitchen, an inviting living area, comfortable and spacious bedrooms. With a short distance to local uptown shops and a welcoming ambiance, it's an ideal choice for a temporary stay. Plenty of space to park a motorhome, boat or trailer and fun entertaining.

Guest favorite

Townhouse in Des Moines

5 out of 5 average rating, 23 reviews

Des Moines' Finest

Welcome to our Airbnb in the heart of Des Moines, Iowa, where luxury meets Midwest comfort, and city views await you at our home. Situated on the southside of downtown just a few miles from the airport, you'll find yourself within striking distance of the city's finest attractions, restaurants, and entertainment options, making it the ideal choice for your stay in Iowa's capital. This modern three-story condo was just newly built and we take pride in maintaining it to the highest level.

Superhost

A spacious kitchen is presented with sleek black and white cabinetry. Modern appliances, including a black refrigerator and a microwave, are visible. The tile floor features a classic pattern, while ample counter space is available for meal preparation. Natural light filters through the nearby window.

Home in Des Moines

5 out of 5 average rating, 4 reviews

Getaway on Grand King Bed

Stylish Stay Near the Fairgrounds & Downtown! Experience comfort and convenience in this fully remodeled 3-bed, 2-bath home. Perfectly located near the Iowa State Fairgrounds, downtown, and major interstates, it’s your ideal base for exploring the city. Enjoy a modern kitchen, cozy living spaces, free Wi-Fi, and a spacious backyard. Whether you're here for the fair, work, or play, this home has everything you need for a relaxing stay. Book now and make it your home away from home!

Guest favorite

A modern kitchen island is showcased with a sleek countertop. A small succulent and a vase with greenery sit on the surface, accompanied by two white plates and bowls. Natural light filters through large windows, creating a bright and airy ambiance.

Apartment in Winterset

5 out of 5 average rating, 9 reviews

Luxury 2 Bed/2 Bath Condo

Experience luxury in this 2-bedroom, 2-bath condo on Airbnb, designed for relaxation and comfortably sleeping four guests. Highlights include an elegant fireplace for cozy evenings and a fully equipped kitchen for gourmet meals. Nestled in a prime location, this condo promises both comfort and convenience, making it an ideal choice for travelers seeking a blend of luxury and practicality. Enjoy unwinding by the fire or exploring nearby attractions for an unforgettable stay.

Guest favorite

A serene view of a tranquil pond is framed by two trees casting dappled shadows on the lush green lawn. The water reflects the surrounding greenery, creating a peaceful outdoor environment. A pathway can be seen leading toward the pond, enhancing accessibility to the natural setting.

Townhouse in Panora

4.97 out of 5 average rating, 33 reviews

Spacious Getaway Townhome on Lake Panorama/Golf

Need a nice, relaxing week on the lake & golf course? Look no further! This is a spacious, 2 bedroom/2 bathroom townhome that has room to fit more. Walk out the back patio to Panorama's Golf Course hole 5 with a view of the lake and pond. Only a two minute walk to the swimming pool ($5/day fee), gym, conference center & Links Restaurant and Bar. Pickle ball, basketball, tennis, playground and beach access all within a 10 minute walk as well. #LocationLocationLocation

Superhost

A well-lit basement area features a granite bar with four high-backed chairs. Two wall-mounted televisions are positioned for entertainment, while a cozy seating arrangement is visible in the background. Neutral-colored walls and a warm wooden floor create a welcoming atmosphere.

Home in Des Moines

5 out of 5 average rating, 5 reviews

Cozy Des Moines Waterbury Home

Welcome to your dream vacation rental in Waterbury! This stunning house is located in the desirable Waterbury neighborhood, offering a peaceful and picturesque setting for your stay. Plus, you'll have the added advantage of being conveniently situated next to the renowned Willow on Grand event center and a 3 minute walk to The Val Air Ballroom. Get ready to indulge in a truly memorable experience! Relax with the whole family at this peaceful place to stay.

Guest favorite

A spacious ground-floor unit is shown beside a swimming pool, surrounded by greenery. The building features multiple outdoor seating areas and is set against a backdrop of trees and landscaped gardens.

Apartment in West Des Moines

4.83 out of 5 average rating, 36 reviews

Inspiring & Calm Elevated Scenic View

Ground-Floor Unit. Relax at this unique and serene retreat. We carefully select each of our units to ensure your convenience, safety, and comfort. Our units boast new furnishings with no expense spared, featuring top-quality linens, high-speed internet, fully equipped kitchens, king-sized beds, private balconies, and included parking garage space with every reservation. As a local company, we are on hand to assist you throughout your stay.

Guest favorite

A cozy corner is highlighted by a rattan chair adorned with an orange cushion, complemented by a small wooden table. A decorative wall hanging adds visual interest, while a vibrant plant brings a touch of nature indoors. The backdrop features warm wooden paneling.

Home in Ankeny

4.95 out of 5 average rating, 130 reviews

Historic Home on 4 Acres - Hot Tub, Pool, Tiki Bar

Our 1948 vacation home is on 4 acres & boasts 3 bedrooms, 3 full baths, 2 half baths, Bridal Suite (4th bedroom), 70s TV/Game Room, Tiki Bar, & Children's Playroom. Outside we have a pool (guaranteed to be open 5/26 - 9/5, but will do everything possible to have it open well before and after those dates based on weather!), hot tub (year round). Located 15min away from Downtown DSM & a mile away from a grocery store/restaurants.

Top guest favorite

A newly installed hot tub is visible, featuring a spacious design that accommodates up to seven guests. Multicolored LED lights illuminate the water, enhancing the inviting atmosphere. The sleek surrounding area highlights the modern features of the installation, ideal for relaxation and leisure.

Home in Urbandale

4.96 out of 5 average rating, 111 reviews

Suburban Oasis with Hot Tub

Sleeping 12 people, 4 bedrooms, 7 beds, 3.5 bathrooms, this comfortable suburban home offers a new hot tub with Bluetooth speakers, and fenced in yard. Walk out basement includes an air hockey table, day bed, recliners, and separate kitchen area with new mini fridge to relax day to night with the family. Fiber WiFi available and smart TVs in the living areas to enjoy any entertainment. This home is the ideal place to gather.

Guest favorite

A modern bathroom features a dual sink vanity with a dark wooden cabinet. Above the sinks, a well-lit mirror is flanked by elegant fixtures. Soft, rolled towels are neatly arranged in a basket, and a plush mat adds comfort underfoot. A glass shower is visible in the background.

Home in Ankeny

4.9 out of 5 average rating, 82 reviews

Spacious home, fast wifi, quiet neighborhood

Perfect for group getaways, this stylish space offers a comfortable retreat. Tailored for both business travelers seeking a long-term stay and families looking for a spacious and relaxing escape. Discover a welcoming home that combines modern design with convenience. Explore nearby attractions or unwind in the ample and thoughtfully furnished living areas. Your ideal Airbnb experience awaits!

Guest favorite

The exterior of a two-story duplex features a light-colored façade with dark shutters. The entrance is marked by a spacious front porch with seating. Surrounding the house are well-kept flower beds and a manicured lawn, bordered by trees providing shade in the background.

Townhouse in Windsor Heights

4.82 out of 5 average rating, 11 reviews

The Cozy Retreat

Welcome to this Smoke free duplex that is centrally located to anywhere you are wanting to go. This prime location is close to grocery stores, coffee shops, nail salon, parks, trails, and more Its perfect for your leisure or business travels as you will find comfort at every turn. Escape the hustle and bustle and book your vacation here and enjoy an relaxing and peaceful experience.

Top guest favorite

The apartment entrance features a central door adorned with playful illustrations, flanked by two large windows. Pink wooden doors lead into a welcoming space, while potted plants with colorful flowers add a touch of nature to the entryway.

Apartment in Stuart

5 out of 5 average rating, 104 reviews

The 1894 by Doe A Deer | 2 br, 1 bath apartment

Welcome to The 1894 by Doe A Deer - a newly renovated 2 bedroom spacious apartment located in historic downtown Stuart! Enjoy restaurants, boutiques and coffee just steps from the front door. Relax and enjoy the view from your new favorite small town spot. Perfect for getting ready with your wedding party, families, girls trips, anniversaries & more! We can’t wait to host you!