House vacation rentals in Des Moines
Find and book unique houses on Airbnb
Top-rated house rentals in Des Moines
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Des Moines house rentals
House rentals with free parking
Home in Des Moines
4.98 out of 5 average rating, 175 reviewsThe Cow Tipper: Spa • Game Room • BBQ • Fire Pit
Home in Waukee
4.84 out of 5 average rating, 107 reviews•5 bedroom 2 full bath stay in Paradise King bed•
Home in Des Moines
4.88 out of 5 average rating, 118 reviewsCozy 4br Home - Close To Downtown!
Home in Urbandale
4.81 out of 5 average rating, 137 reviewsCozy home with 4 bedroom in Urbandale
Home in West Des Moines
4.79 out of 5 average rating, 107 reviewsBudget friendly upstairs apartment in duplex!
Home in Des Moines
4.91 out of 5 average rating, 348 reviewsCozy Home in the Heart of Des Moines
Home in Des Moines
4.85 out of 5 average rating, 137 reviewsYour home away from home.
Home in Des Moines
4.86 out of 5 average rating, 250 reviewsCozy House close to Drake/Downtown w Patio+Yard!
House rentals with a pool
Home in Ankeny
4.86 out of 5 average rating, 42 reviewsComfortable and Spacious Five Bedroom Home
Home in West Des Moines
4.64 out of 5 average rating, 14 reviewsWest Des Moines modern mansion!
Home in Ankeny
New place to stayDreamy Peaceful Retreat - Spa
Home in West Des Moines
5 out of 5 average rating, 7 reviewsNew Neat Nascent & Neighborly
Home in Urbandale
4.96 out of 5 average rating, 55 reviewsThe Estate
Home in Des Moines
4.79 out of 5 average rating, 66 reviewsSpacious Home w/ Hot Tub & Near Attractions
Weekly house rentals
Home in Carlisle
4.85 out of 5 average rating, 20 reviewsQuiet Country home, nature & fishing -5min to city
Home in Clive
4.88 out of 5 average rating, 77 reviewsFamily-Oriented 5 BR Home with Hot Tub & Game Room
Home in Des Moines
4.66 out of 5 average rating, 68 reviewsCute 2-bedroom / 1 bath house completely remodeled
Home in Ankeny
4.98 out of 5 average rating, 64 reviewsSaylorvilla ~ Tesla Charger
Home in Norwalk
5 out of 5 average rating, 217 reviewsModern Farmhouse with Optional Venue Rental
Home in Winterset
5 out of 5 average rating, 28 reviewsThe Little Red House
Home in Des Moines
4.86 out of 5 average rating, 100 reviewsDisco Dreamhouse (Fully Fenced in Yard!)
Home in Winterset
4.98 out of 5 average rating, 238 reviewsDebbie’s Komfy Diggs Winterset
Quick stats about house rentals in Des Moines
Total rentals
400 properties
Total number of reviews
22K reviews
Family-friendly rentals
280 properties are a good fit for families
Pet-friendly rentals
160 properties allow pets
Rentals with dedicated workspaces
250 properties have a dedicated workspace
Wifi availability
390 properties include access to wifi
Destinations to explore
- Ames Vacation rentals
- Pella Vacation rentals
- West Des Moines Vacation rentals
- Waterloo Vacation rentals
- Ankeny Vacation rentals
- Cedar Falls Vacation rentals
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- Lake Red Rock Vacation rentals
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- Rentals with a fire pit Des Moines
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