Hotel vacation rentals in Los Santos Province

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Top-rated hotel rentals in Los Santos Province

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Guest favorite

An aerial view captures a cluster of six dome suites arranged in a circular layout, set against a backdrop of rolling hills and distant water. Each dome features a smooth, rounded exterior and is surrounded by a spacious deck and natural landscape.

Resort in Cañas

5 out of 5 average rating, 9 reviews

Standard Suite

Representing each of the seven chakras and set in a circle, our suites are the ideal environment for alignment, balance and creativity. Each with a different spectacular view: the rolling hills of Cañas, sunrise, ocean, Isla Cañas and sunset, these domes offer A/C, an indoor loft, ensuite bathroom with hot water, and a private deck with star gazing net and/or outdoor living room. Suites can be arranged with 2 king beds, 1 king & 2 twin beds or 4 twin beds. No children under 16 allowed or pets

A private balcony is furnished with a dark wicker seating area and a glass-top coffee table. Greenery surrounds the space, offering a view of the outdoors. Hummingbird feeders are visible on the wall, complemented by a natural wooden structure.

Hotel room in Pedasí

4.6 out of 5 average rating, 5 reviews

Ocean view hotel near beach.

The Hummingbird Inn is located just a two minute walk to Playa El Toro (Bull Beach). 3 kms from Pedasi. From our lovely upper rooms you can see the ocean. Hummingbirds frequent our grounds and feed from feeders placed around the hotel. Rooms have a door on each side for cross breezes. Upper rooms each have a private balcony Rooms include one queen bed, TV, large shower with hot water, small fridge, air conditioning. Shared kitchen area available and laundry facilities Sorry there is no pool

Guest favorite

The vibrant property features a spacious pool illuminated by soft lighting, surrounded by tropical foliage. A well-lit, two-story building with a thatched roof stands nearby, showcasing multiple balconies. String lights add a warm ambiance to the outdoor area.

Hotel room in La Enea

4.74 out of 5 average rating, 43 reviews

Private, open concept room with pool/beach access!

Looking for a private, open concept room with pool and beach access? The room has a queen size bed, bunk bed, and sofa bed with private bathroom. The 2nd floor balconies have pool/ocean views. The room is located at Playa Guarare, but is only a 20 minute drive to Las Tablas and 35 minutes to Chitre. On-site restaurant can provide daily meals. 2 minute walk to the beach and 3 minute walk to the port where you can hire a boat for fishing/whale watching. Hammocks and picnic tables available too!

Guest favorite

A private porch is featured, showcasing wooden flooring and a rocking chair. A hammock is suspended nearby, surrounded by lush greenery. Potted plants add natural accents to the space, while warm wood tones create a comforting atmosphere.

Hotel room in Cambutal

4.8 out of 5 average rating, 20 reviews

Cedro Espino Cabana, Ocean view, Steps From Beach

No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.

Superhost

A spacious porch is visible through the open French doors, featuring comfortable seating with a hammock and a lounge chair. Lush greenery and palm trees are present in the background, along with a view of the tranquil shoreline peeking through the landscape.

Hotel room in Playa Venao

4.75 out of 5 average rating, 4 reviews

Ocean View Private King Bed Room @ Villa Marina

Amamos el océano tanto como tú. Por eso hemos creado el lugar perfecto para que disfrutes de las olas y de todo lo que el Pacífico panameño tiene para ti en las playas de Pedasí. Villa Marina Lodge es un lugar único en su categoría. Ubicado en Playa Venao, un paraíso internacional del surf, ofrece habitaciones cómodas y amenidades de primera para que tu viaje a la playa sea siempre una experiencia especial. Un lodge, a diferencia de un resort, es más relajado, casual y acogedor.

Superhost

A shaded swing bed with soft cushions is situated under a thatched roof. The lush green lawn leads to the beach, where ocean waves can be seen gently lapping the shore. Nearby palm trees provide a tropical ambiance.

Hotel room in Playa Venao

4.9 out of 5 average rating, 10 reviews

Marea - Ocean View Room with King Sized Bed

This stunning family room features a comfortable king sized bed and one single bed. Ground floor, with idyllic ocean views, walk out to a gorgeous shared pool and calming space right on the beach. Steps away is El Sitio restaurant which offers a varied and delicious menu, perfect for traveling families. The shared lounge features a serene setting and relaxing vibe, with fun for everyone nearby. A 10% tax will be collected separately as Airbnb do not collect tax on behalf host.

Superhost

A spacious living area features large glass doors that open to a wooden deck and green surroundings. Pendant lighting hangs above a kitchen counter with three stools, while a low wooden table and cushions are placed on the floor, providing an inviting space to relax.

Private room in Playa Venao

5 out of 5 average rating, 4 reviews

Dos Mares Venao Village - Bungalow

Desconecta de tu rutina y disfruta de la naturaleza. Nuestras Cabañas son amplias, cómodas, con mucho estilo y de alta calidad. Con 1 habitaciones con cama King, una habitación con dos camas twin, sala y cocina hay espacio para toda la familia. Además tenemos ducha externa, televisión, y una terraza amplia. En nuestro bar puedes disfrutar de los mejores desayunos. Si deseas también te lo llevamos directo a tu cabaña - como lo deseas!

Superhost

The villa is situated amidst lush greenery, showcasing a modern design that blends with the surrounding jungle. Spacious outdoor areas are visible, with seating arrangements under the shade of trees, inviting a relaxed atmosphere for guests to enjoy their surroundings.

Hotel room in Cambutal

4.94 out of 5 average rating, 16 reviews

Boutique Inn_The Hill 2_Private Entry_Tripple_+16

The Hill Panama, our Boutique Inn Adult Only (16+) is proud to be featured on Architectural Digest Magazine, located in the heart of enchanted Cambutal Beach, just a 5 five-minute walk to the beach, surrounded by several surf spots, balance between mountain and sea, hidden amongst the jungle canopy. This listed Room 2 was designed as a boutique hotel room with separated private entry and communal kitchen.

A small, modern cottage is presented, featuring a welcoming front porch with a hammock and a dining set. A concrete pathway leads to the entrance, surrounded by greenery. Chickens can be seen roaming nearby, adding to the tranquil, rural setting.

Private room in Las Tablas

4.75 out of 5 average rating, 8 reviews

Hotel Villas Don Pablo / Las Tablas Villa No. 2

Hostal Villas Don Pablo is an accommodation where you will be in contact with nature, where you can relax alone or with your family and pets. Just 11 minutes from our hostel we have a nice, clean and safe beach. The treehouse village is only 2 minute drive to our hostel. Our cabins have everything you need for a pleasant visit. We have WiFi throughout the hostel.

Superhost

The image depicts a clear, turquoise salt-water swimming pool with gentle ripples, reflecting the blue sky. In the background, a palm tree sways beside an open view of the beach and ocean, framed by a shaded dining area under a roof.

Private room in Las Tablas Abajo

4.79 out of 5 average rating, 19 reviews

Rose Room for 2 at Casa Lassini - Beachfront!

Beach view economy room at Playa Las Comadres. Each room has Starlink Internet with 3-hour battery backup, Smart TV with Netflix, A/C, full sized refrigerator, microwave, toaster, coffeemaker, coffee and supplies. Private bath. A 13-minute drive from Las Tablas.