House vacation rentals in South Carolina

Find and book unique houses on Airbnb

Top-rated house rentals in South Carolina

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite

A bright living room features large windows allowing natural light to fill the space. A comfortable white sofa is paired with a wooden coffee table, while a cozy rocking chair sits nearby. Books are neatly arranged on a shelf above the fireplace, adding a homely touch.

Home in North Myrtle Beach

4.93 out of 5 average rating, 123 reviews

My Favorite Beach House

My favorite beach house is a patio family home in North Myrtle Beach. A 6 minute walk, 3 blocks to the beach with a golf cart (not included ) parking place inside the patio. Bright & airy, decorated with personal furniture and belongings bought from all over the world, the owner is a well known photojournalist. There are 3 bedrooms & 2 full baths, a stocked kitchen, outdoor patio w/charcoal grill & outdoor shower. Located in the center of Crescent Beach which is a historic local beach community.

Top guest favorite

A spacious living room features vaulted ceilings and a ceiling fan. Two leather sofas face a wooden coffee table, with a decorative bowl in the center. A 55-inch Smart TV is mounted above a modern fireplace, and large glass sliding doors provide natural light and access to the backyard.

Home in Hilton Head Island

4.98 out of 5 average rating, 118 reviews

“Sea La Vie” 3BR, Sea Pines, Walk to Dining, Shops

Privately-owned 2000 SF one-level home sits on a wooded corner lot conveniently located inside the entrance of Sea Pines Resort. This 3 BR, 2BA home was extensively renovated in August 2020, with inviting French-inspired coastal decor for a relaxing cozy feel. "Sea La Vie" chalet is within walking distance to grocery stores, shops, and restaurants. A short drive or bike ride takes you to the private Beach Club, housing oceanfront dining and bar, upscale facilities, and wide beaches. Bienvenue!

Superhost

A serene beach scene at sunset showcases gentle waves lapping against the shore, reflecting hues of orange and purple. Silhouettes of buildings line the coast in the background, contributing to the tranquil atmosphere of the evening sky.

Home in North Myrtle Beach

4.75 out of 5 average rating, 114 reviews

Charming Family Friendly Beach Home, Fenced Yard

Renovated 4BR, 3BA home in the quiet, quaint Windy Hill neighborhood of North Myrtle Beach! Conveniently located near Restaurant Row, shopping, bars, Barefoot Landing, and top golf courses. Walk or take a short golf cart ride to the beach (we can refer you to rentals nearby)! Enjoy our private fenced-in backyard with a brick grill, firepit, and lit seating area. A true home away from home in the heart of it all! We are family & pet-friendly, and can accommodate up to 10 guests and 2 fur-babies.

Guest favorite

A charming two-story townhouse is depicted with a bright yellow exterior and crisp white trim. Black shutters frame the windows, complemented by a welcoming front porch adorned with seating. The neighboring houses feature pastel blue and green hues, adding to the colorful community appeal.

Home in Myrtle Beach

4.9 out of 5 average rating, 409 reviews

Beach Style Cottage One Block To Beach!

*** You can find my other two listings by clicking on my owner badge! *** The total price includes: base rental fee from host, $100 cleaning charge by the cleaning company, SC tax amd Airbnb service fee. *** Winter season long term rental (1-4 months) are available from November to Febrary. Please ask Victor for the discounted rate. Just One Block from Beach! Beautifully decorated, beach style, 2 bed, 2 bath townhouse, with furniture, electronics & appliances, accommodates 7 people.

Superhost

A large back deck features a table with chairs and a bright blue umbrella, providing shade. The view overlooks the lake, dotted with bare trees and boat docks in the distance. Soft natural light enhances the inviting outdoor space.

Home in Anderson

4.86 out of 5 average rating, 202 reviews

Lake Living with Amazing Views of Lake Hartwell

Stunning lake views in highly popular The Shoals in Portman Marina located on Lake Hartwell. Bring your pets with you, we are pet-friendly, and they'll love running around the fenced in backyard. Very large back deck overlooking the lake while you have morning coffee, grill or just relax! We also are located in a very nice, quiet neighborhood in cul de sac. Short drive to Clemson University for games or student/family events. Also, short drive to downtown Anderson and Anderson University.

Guest favorite

A bright bedroom features a spacious bed with a colorful patterned bedspread and decorative pillows. Two windows allow natural light to fill the room. A bedside table stands beside the bed, and a sliding glass door leads to a balcony or outdoor area.

Home in Folly Beach

4.94 out of 5 average rating, 128 reviews

Beautiful Beach House. Outstanding Location.

Beautiful Beach House. Sleeps 8. Outstanding location. 3 bedroom, 2 bath beach house offering a view of the ocean. Access to the beach is directly across the street. Less than 200 feet to the ocean. Large great room and large dining area. Amenities include high speed wireless internet, 65" HDTV in the living room, Central AC, washer and dryer, full kitchen.1 king, 1 queen, 2 doubles, sleeper sofa. Outdoor shower to rinse off after a day at the beach. SC Business License: LIC-2-19-202662

Guest favorite

A modern three-story home is set among lush greenery, showcasing a classic white exterior and an inviting front porch. An American flag gently flutters, and landscaped elements, including palm trees, complement the home's fresh, vibrant appearance.

Home in Mount Pleasant

4.93 out of 5 average rating, 156 reviews

Lowcountry Lux / 5 min to Beach / 7 min to Dtwn

Luxurious & comfortable home located in Mt. Pleasant; located walking distance to a grocery store, a mile from Shem Creek w/ several new chic restaurants, a 2-min ride to restaurants & shops, 5-min to the nearby beach on Sullivan's Island, and 10 minute drive to downtown Charleston. You will feel right at home in this luxurious 3-story home with a brand new 82" TV, a WFH area, BBQ grill, & outdoor seating area. Come experience lux modern beach living and all Charleston has to offer!

Guest favorite

A bright living area features a spacious sofa centered against a wall with two mirrors. Two gray accent chairs flank a coffee table, with a vase of flowers providing a touch of color. Natural light streams in through the window, illuminating the hardwood floor and area rug.

Home in Mount Pleasant

4.89 out of 5 average rating, 483 reviews

Beach+Downtown ★Walkable Old Village Luxury Style2

Best of Both worlds--3 minutes to Downtown Charleston & Sullivan's Island Beach! Mt Pleasant is Rated the Best Place to Live in SC! Enjoy Downtown Mt Pleasant Amenities. Old Mt. Pleasant in a Marsh-front Community. Beautiful 100 year-old Oak Trees! Walk to Shem Creek Restaurants & Marina, Steps to Old Village, Grocery stores, coffee shops, shopping, Red Drum Gastro Pub, New Mt P. Farmers Market. Relax in wonderful large private backyard under tree canopy. ST250064 BL: 20123990

Superhost

A hot tub with illuminated jets is positioned outdoors, surrounded by warm string lights. The water's surface is calm, inviting relaxation. Beyond the hot tub, a cozy seating area is visible, featuring two chairs and a small table, enhancing the outdoor appeal.

Home in Ladson

4.9 out of 5 average rating, 166 reviews

Charleston HotTub FirePit FirePlace Patio Hammock

👍PRIME CENTRALIZED LOCATION to explore all Charleston has to Offer! ✅ NO Cleaning Fees! ✅ 2 mins to Summerville Medical Center ✅ Featured in Relative Race Reality TV show! ✅ 10 mins from I26 ✅ 35 mins from downtown Charleston and beaches🏖 ✅ 18 mins to Airport/Convention Center/Performing Arts ✅ 3 mins to Publix Grocery/restaurants ✅ Hot Tub 💦 ✅ Fire🔥Pit ✅ BBQ 🍔 Grill ✅ Fire🔥Place ✅ Hammock 🌴 ✅ High Chair & Pack n Play 🍼 ✅ Air Hockey Table 🏒 ✅ K Cup/Coffee Pot ✅ EV plug

Guest favorite

The exterior of the house showcases a two-story design with light-colored siding and multiple decks. A long set of white stairs leads to the upper level. Lush greenery surrounds the property, including palm trees and a manicured lawn.

Home in Isle of Palms

4.91 out of 5 average rating, 121 reviews

Amazing Location, across the st. from the beach!

Located directly across the st. from the beach, w/public access! Fully fenced, pet friendly. 4 bd - sleeps 10 comfortably, 2.5 bths. Bright open airy design. Huge living room w/high vaulted ceilings. Eat-in kitchen & newer appliances. Formal dining rm w/lots of glass & great views. 3 front porches-1 screened. 3 Decks. French doors in up. bds lead to outdoor sitting areas. Close to awesome restaurants, shopping, food stores & so much more! ONLY WEEK LONG MIN STAYS IN SUMMER

Guest favorite

A light-filled living area features exposed wooden beams and a mix of cozy seating options, including a brown leather sofa and two blue velvet chairs. A wooden table sits at the center, accompanied by decorative items and plants. Art pieces adorn the walls, adding a touch of character.

Home in Charleston

4.98 out of 5 average rating, 137 reviews

❤️ of Charleston - Luxurious & Rustic -Near King!

Completely Renovated House - 1block from King Street! (Brand New Listing! - Rare Find!) * 3 bedrooms +2 full bunk beds & 2 full bathrooms * Brand new Construction - Heavily insulated and quiet inside! * High End Kitchen! * Walk Score 98 ('Very Walkable') * 1 Block From King Street * Private Outdoor Piazza + Outdoor Terrace * Off Street Parking for 2 vehicles * Onsite washer's & dryer's * Safe neighborhood in awesome location - near all the best restaurants and bars!

Guest favorite

The outdoor area features a spacious deck adorned with a wooden pergola, providing shade for seating and dining. Hammock chairs are suspended, and ambient lighting is visible among the greenery, creating a relaxing atmosphere. The well-maintained yard showcases stone pathways and lush grass.

Home in Charleston

4.86 out of 5 average rating, 289 reviews

Hot Tub•Game Room•King Bed•WiFi•W/D•Full Kitchen•

Discover the perfect getaway for families and couples with our spacious 2-bedroom home in Downtown Charleston. **Please message us and ask about our seasonal discounts for **Weekly & Monthly Rentals!** Featuring: -Fully Equipped Kitchen -Large Covered Porch W/Outdoor Dining -Hot Tub -Game Room -King Bed -5 Smart TVs -High-speed Wifi -Fully Fenced- In Backyard -Free Off-Street Parking -Washer/Dryer -Family & Pet Friendly