Vacation rentals in Wapello

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Top-rated vacation rentals in Wapello

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Le Claire

4.93 out of 5 average rating, 158 reviews

Great River Road with Hot tub views!

Located on historical Great River Road our house is just minutes from charming downtown Leclaire and home of American Pickers. Enjoy stunning views of the Mississippi river during your morning coffee and watch the barges drive by! If you enjoy fishing you can fish right off the banks! Did we mention hot tub views?! Nothing beats a night in the hot tub on the river! We provide all amenities of a home away from home. Plenty of space allowing you to relax comfortably with all of the family.

Guest favorite

Apartment in Davenport

4.77 out of 5 average rating, 641 reviews

Spacious Village Victorian

Spacious Beautiful 1890 Victorian house on a hill overlooking the Mississippi River. The perfect quiet getaway for singles, couples or small groups. Close to Restaurants, bars, boutiques, and a sprawling bike path. This apartment is the lower level of a duplex. I live upstairs. Fire pit in the summer with a view of the Mississippi River. Full kitchen, dining room, living room. Feel free to spread out and make yourself at home in this spacious blissful one bedroom with a king sized bed.

Superhost

Place to stay in Keosauqua

5 out of 5 average rating, 3 reviews

The Tiny Nest, A Unique Space on Main Street!

Welcome to THE TINY NEST! Our cozy apartment is designed to be your perfect retreat, offering comfort and convenience right near the Des Moines River. Nestled behind THE ROOST LAUNDROMAT, you'll find yourself in the heart of Keosauqua, Iowa, with easy access to local attractions. Explore the charm of Keosauqua, where you can wander through 11 delightful villages featuring specialty shops, dining options, antiques, and a community pool. THE TINY NEST is your perfect base. Enjoy your stay!

Guest favorite

Cottage in Le Claire

4.97 out of 5 average rating, 212 reviews

Grasshoppers Guest House Too, cozy, cute, cottage!

This cozy cottage is 1000 sq. feet of charm. You are in the heart of downtown, historical Le Claire. Your home away has everything you will need for your stay. The porch overlooks downtown, nestled in with views of the Mississippi River. Shops, dining, brewery & distillery all to enjoy. visitleclaire.com has monthly activities & festivities. Birthplace of Buffalo Bill Cody & home to Mike Wolfe on American Pickers. You may even see him unloading treasures at his shop Antique Archaeology!

Guest favorite

Home in Nauvoo

4.88 out of 5 average rating, 66 reviews

Historic Hart Home Across from Temple-Sleeps 8

Location, Location, Location. Welcome to the historic Hart House, located directly across from the Nauvoo Temple, and a short walk to local shops and restaurants. The home sleeps 8 with 1 King, 2 Queen, and 1 bunkbed. Here you will be able to sit on the porch or a comfortable chair inside and enjoy views of the Temple, Mississippi River and surrounding country-side. A unique home owned by the Hart family for many generations. Period woodwork and esthetics throughout the house.

Superhost

Home in New Boston

4.91 out of 5 average rating, 33 reviews

Cute Cottage on the Bay

This charming cottage perfectly combines comfort and nature with direct access to Boston Bay at the bottom of a winding set of stairs. Soak in the amazing views from the new deck. The house has everything you need for your rustic getaway. There is also a convenience store/gas station in town and 2 bars/restaurants. Bring your boat or jet ski to the launch just down the road on the Mississippi at one of the public launches at the riverfront park and campground.

Guest favorite

Treehouse in Oxford

4.96 out of 5 average rating, 26 reviews

Creekside Treehouse & Lavender Farm

Welcome to our charming treehouse retreat overlooking a creek, a working lavender farm. This Airbnb offers a unique blend of charm, modern comfort, and lots of wildlife. The treehouse features a cozy interior with panoramic views, a king-sized bed, spacious deck, heated floors, fiber internet, and more. Ideal for a romantic getaway or retreat, our treehouse promises a memorable stay amidst the beauty of nature. We look forward to welcoming you!

Guest favorite

Home in Davenport

4.99 out of 5 average rating, 170 reviews

Davenport East Village Retreat-McClellan Heights

1920 stately, charming home in historic McClellan heights on secluded lot surrounded by trees and wildlife. View of the river Centennial bridge lights In fall, bugle calls from Arsenal at 6:30 am 9:30 and 10:00 pm. Very quiet safe neighborhood on narrow low traffic cross street. Walking distance to bars (live music on weekends) restaurants, shops, kwik shop, coffee shop, Lindsey Park playground, water taxi on the river, 70 mile bike trail.

Guest favorite

Apartment in Le Claire

4.93 out of 5 average rating, 299 reviews

Wide River Winery Inn

Located in downtown historic LeClaire, a quaint but lively town on the Mississippi River. Two blocks from the American Pickers and a short walk to The Crane and Pelican and the La Ragazza Tuscan Kitchen & Bar. Up the street is Mississippi River Distilling Company and the delicious Brewery and next door is Cody Road Coffee. Guests are invited to sample our award winning wines and to choose a complimentary bottle of wine to enjoy.

Guest favorite

Cottage in Port Byron

5 out of 5 average rating, 123 reviews

River Current's Cottage

River Current's Cottage is a hidden gem tucked on the banks of the Mighty Mississippi River. This cozy cottage has magnificent views of the river, no matter what time of year you chose to stay the views & cottage will offer you endless relaxation and enjoyment. With wonderful options for dining just minutes away in Port Byron or driving a few more minutes to LeClaire, IA you can truly make this a relaxing getaway.

Guest favorite

Home in Iowa City

5 out of 5 average rating, 31 reviews

The Stuart House near downtown Iowa City

Lovingly remodeled and newly listed, this cozy bungalow is located in a historic neighborhood close to downtown Iowa City. Within steps to the bus line, blocks from a delicious bakery, a 20-minute walk downtown, and slightly over 2 miles to UIHC, this snug home is centrally located near everything Iowa City has to offer! Discounts for stays of a week or longer. Pet-free home.

Guest favorite

Home in Le Claire

4.99 out of 5 average rating, 115 reviews

The LeClaire River Chateau

A beautifully remodeled 3 bedroom 2 bath home with an unobstructed view of the Mississippi River. Fantastic location just steps from the shops and restaurants. Perfect for larger groups, sleeping 9 guests. Whether visiting LeClaire with family, looking for a get-together rental, or a weekend away with the girls - the LeClaire River Chateau is the place for you.