House vacation rentals in Charleston County

Find and book unique houses on Airbnb

Top-rated house rentals in Charleston County

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Mount Pleasant

5 out of 5 average rating, 108 reviews

Rockin’ Robin - Family sized great location!

Beautifully designed Open Floor plan 5 Bedroom/ 4.5 Bathroom home that is in an incredible location. So Close to everything! Each Room has a Comfortable Queen bed and only Two Rooms share a bathroom. Every other Room has their own En-Suite. Large Chefs Kitchen that is open to the other areas of the home for socializing. Great Man cave in the Garage with Lots of games. Relax in the Great room with Big windows for Natural Light TOMP STR Permit No. ST250034 Mt Pleasant Business License #20107744

Guest favorite

Home in Folly Beach

4.96 out of 5 average rating, 165 reviews

Lux Beach Bungalow Ocean Views Heated Pool

Relax on the beach. Shower outside. Sip cocktails on one of the porches with beach views. Grill out by the pool. Take a stroll to dinner and enjoy some live music with friends and family. Luxury furnishings and linens. Stay in a home not just an Airbnb. One block from Center Street, you are walking distance to shops, restaurants, bars, the pier, and Bert's corner market. This comes in very helpful as this area is nearly impossible to find parking. Front door to the sand is <300ft. LIC 007914

Guest favorite

Home in Mount Pleasant

4.93 out of 5 average rating, 148 reviews

Lowcountry Lux / 5 min to Beach / 7 min to Dtwn

Luxurious & comfortable home located in Mt. Pleasant; located walking distance to a grocery store, a mile from Shem Creek w/ several new chic restaurants, a 2-min ride to restaurants & shops, 5-min to the nearby beach on Sullivan's Island, and 10 minute drive to downtown Charleston. You will feel right at home in this luxurious 3-story home with a brand new 82" TV, a WFH area, BBQ grill, & outdoor seating area. Come experience lux modern beach living and all Charleston has to offer!

Guest favorite

Home in Isle of Palms

4.96 out of 5 average rating, 161 reviews

Intracoastal water view luxurious family retreat

Enchanting house like no other on the island! Designed for guests who value a five-star experience. This luxury getaway is far from ordinary, it is simply perfect. - Right on the world-renowned Wild Dunes golf course - Only .5 mile from the beach -Enjoy FABULOUS SUNSET VIEWS OF THE INTRACOASTAL WATERWAY from the cozy porches - 3 king beds and 6 single bends - Soak away tension in our romantic 2-person tub or in the 8 person tub - Gym, infrared sauna - Game room: pool and Foosball

Guest favorite

Home in Mount Pleasant

4.89 out of 5 average rating, 466 reviews

Beach+Downtown ★Walkable Old Village Luxury Style2

Best of Both worlds--3 minutes to Downtown Charleston & Sullivan's Island Beach! Mt Pleasant is Rated the Best Place to Live in SC! Enjoy Downtown Mt Pleasant Amenities. Old Mt. Pleasant in a Marsh-front Community. Beautiful 100 year-old Oak Trees! Walk to Shem Creek Restaurants & Marina, Steps to Old Village, Grocery stores, coffee shops, shopping, Red Drum Gastro Pub, New Mt P. Farmers Market. Relax in wonderful large private backyard under tree canopy. ST250064 BL: 20123990

Guest favorite

Home in Isle of Palms

4.91 out of 5 average rating, 116 reviews

Amazing Location, across the st. from the beach!

Located directly across the st. from the beach, w/public access! Fully fenced, pet friendly. 4 bd - sleeps 10 comfortably, 2.5 bths. Bright open airy design. Huge living room w/high vaulted ceilings. Eat-in kitchen & newer appliances. Formal dining rm w/lots of glass & great views. 3 front porches-1 screened. 3 Decks. French doors in up. bds lead to outdoor sitting areas. Close to awesome restaurants, shopping, food stores & so much more! ONLY WEEK LONG MIN STAYS IN SUMMER

Superhost

Home in Ladson

4.9 out of 5 average rating, 163 reviews

Charleston HotTub FirePit FirePlace Patio Hammock

👍PRIME CENTRALIZED LOCATION to explore all Charleston has to Offer! ✅ 2 mins to Summerville Medical Center ✅ Featured in Relative Race Reality TV show! ✅ 10 mins from I26 ✅ 35 mins from downtown Charleston and beaches🏖 ✅ 18 mins to Airport/Convention Center/Performing Arts ✅ 3 mins to Publix Grocery/restaurants ✅ Hot Tub 💦 ✅ Fire🔥Pit ✅ BBQ 🍔 Grill ✅ Fire🔥Place ✅ Hammock 🌴 ✅ High Chair & Pack n Play 🍼 ✅ Air Hockey Table 🏒 ✅ K Cup/Coffee Pot+Tea ✅ 220v EV charging plug

Guest favorite

Home in Charleston

4.98 out of 5 average rating, 134 reviews

❤️ of Charleston - Luxurious & Rustic -Near King!

Completely Renovated House - 1block from King Street! (Brand New Listing! - Rare Find!) * 3 bedrooms +2 full bunk beds & 2 full bathrooms * Brand new Construction - Heavily insulated and quiet inside! * High End Kitchen! * Walk Score 98 ('Very Walkable') * 1 Block From King Street * Private Outdoor Piazza + Outdoor Terrace * Off Street Parking for 2 vehicles * Onsite washer's & dryer's * Safe neighborhood in awesome location - near all the best restaurants and bars!

Guest favorite

Home in Mount Pleasant

5 out of 5 average rating, 219 reviews

Upscale EARL CRT 3-bdrm Old Village/Shem Creek

STR PERMIT #ST240148 BUSINESS LICENSE #32844 3-bdrm Earl's Court neoclassical upscale home, nestled in the heart of the historic Old Village, offering the charm of low country living. Just a block from Shem Creek bars & restaurants, Old Village shops & eateries, Alhambra Hall, Pitt St Bridge, and a weekly all food Farmer's market, featuring low countries finest! The Arthur Ravenel Bridge, downtown Charleston, Sullivan's Island & IOP beaches are all bike riding distance.

Guest favorite

Home in Folly Beach

4.93 out of 5 average rating, 242 reviews

Folly Vacation 204 Getaway, Relax & Unwind

This unique Spanish-style 2 bedroom, 1 1/2 bath beach house is in a quiet residential area with an easy walk to all the restaurants, shops and the ocean. Respectfully renovated to maintain its historic integrity, you’ll appreciate the mix of old and new. Dog friendly with a one-time fee of $110 per dog up to 3 nights, and $150 per dog for 4 or more nights. Fee is added once your reservation is confirmed. Rental Registration Number STR22-00313

Superhost

Home in Charleston

4.85 out of 5 average rating, 280 reviews

Hot Tub•Game Room•King Bed•WiFi•W/D•Full Kitchen•

Discover the perfect getaway for families and couples with our spacious 2-bedroom home in Downtown Charleston. **Please message us and ask about our seasonal discounts for **Weekly & Monthly Rentals!** Featuring: -Fully Equipped Kitchen -Large Covered Porch W/Outdoor Dining -Hot Tub -Game Room -King Bed -5 Smart TVs -High-speed Wifi -Fully Fenced- In Backyard -Free Off-Street Parking -Washer/Dryer -Family & Pet Friendly

Superhost

Home in Charleston

4.91 out of 5 average rating, 223 reviews

4BR/4.5BA - Prime Location - 2 Blocks to King ST

Beautiful 4 Bedroom/4.5 Bath Home in the Heart of Downtown! - 4 Master Bedrooms w/ En-Suite Bathrooms, + pullout sofa bed available - 2 Blocks from the iconic King Street - Off-Street Parking Provided - Walk to Everything! YOURPAD Charleston - Save On Your Stay! With over 75 eccentric homes throughout the heart of downtown Charleston, we encourage you to search YOURPAD Charleston on the web to view special offers.